5 Must Do Things near the Texas Medical Center

An aerial view of the Texas Medical Center with Downtown in the background
Explore all that TMC offers with our Must Do guide | Courtesy of Texas Medical Center

In our Must Do Things Around Greater Houston series, we take a look at Houston’s vast array of communities, neighborhoods and destinations to bring you five fun, tasty, surprising and enticing reasons you should give each one a visit.

Just south of the Museum District, the Texas Medical Center is the largest medical complex in the world, hosting over 60 medical institutions and home to some of the brightest minds in medicine.

The roughly two-square-mile district also rocks a prime location, with proximity to parks, restaurants, a college campus and more.

Here are our picks for 5 must-dos near the Texas Medical Center:

5 Must Do Things near the Texas Medical Center

A view of the "Twilight Epiphany" installation lit purple at sunset
James Turrell’s “Twilight Epiphany” lights up twice daily at Rice University | Photo: Jeff Fitlow; courtesy of Rice University

Stroll the grounds of Rice University

With 300 acres of beautiful, tree-lined campus to cover, Rice University is worth the visit, whether you’re catching a Rice Owls game or simply walking along the 2.92-mile Rice University Loop.

Near the football stadium, James Turrell’s magnificent light and sound installation, Twilight Epiphany, is a must-see.

The acoustically-engineered pyramidal structure is equipped with an LED light sequence that projects onto the roof and evokes the sun’s arc, with performances available at sunrise and sunset everyday (arrive about 15 minutes early to secure your spot).

An overhead view of two large pizza slices next to a bottle of wine
Two Guys serves up massive slices and giant pies near Medical Center | Courtesy of Two Guys Pizzeria

Take down a giant slice at Two Guys Pizzeria

Those looking for a New York–style experience can find one at Two Guys Pizzeria.

The neighborhood pizza joint on Holcombe Boulevard dishes out slices larger than your head, in both classic cheese or with toppings from pepperoni and portobello to buffalo chicken and Hawaiian.

Tack on cannoli or a slice of New York cheesecake for good measure.

A girl feeds ducks on the edge of a lake
One of the city’s signature park experiences can be found in Hermann Park | Photo: Justin Jerkins/365Houston

Explore Hermann Park

Home to the picturesque Japanese and McGovern Centennial Gardens, the Miller Outdoor Theatre, and the Houston Zoo, this epic park is just a short jaunt from the Med Center.

Speaking of the zoo, head there and you’ll find over 6,000 animals in natural habitat-style exhibits, including fan favorites like monkeys, elephants, and cheetahs. Young ones will love the petting zoo; and guests can also feed the giraffes at daily feedings, held at 11am and 2pm.

A darkly lit hall with people passing by dinosaur skeletons
The Paleontology Hall offers a tour through prehistoric history | Courtesy of HMNS

Discover the Houston Museum of Natural Science

There is plenty to uncover at this expansive Museum District gem, which sits at the edge of the Hermann Park roundabout.

Catch a 3D show at the Wortham Giant Screen Theatre; fly through the universe at the Burke Baker Planetarium; marvel at spectacular live and preserved butterflies at the Cockrell Butterfly Center; and tour through a fascinating variety of exhibits covering the areas of astronomy, space science, Native American culture, paleontology, and more.

Tickets are $25 for adults; $16 for ages 3 to 11 (free for ages 2 and under); or check out Free Tuesdays from 5pm to 8pm.

Two bicyclists riding down a path with a bridge and Medical Center buildings in the background
Brays Bayou connects the Medical Center to West Houston, Third Ward and Second Ward | Courtesy of Houston Parks Board

Hit the trails along Brays Bayou

One of Houston’s nine major bayous, Brays Bayou winds 31 miles through the city, starting in Fort Bend County and flowing eastward through the Medical Center and Hermann Park before taking its waters to the Houston Ship Channel, flowing into Galveston Bay.

Thanks to the Bayou Greenways 2020 Project, Brays is among the greenspaces connected through a massive 150-mile network of parks and trails.

Cyclists and pedestrians cross the Bill Coates suspension bridge from the Bayou Parkland area of Hermann Park to access the Brays Bayou Trail’s almost 35 miles of hike-and-bike trails.


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Brooke Viggiano
Brooke Viggiano is a food and lifestyle writer residing in Houston. When she's not contributing to publications like 365 Things to Do in Houston, Thrillist Houston and the Houston Press, she's on the hunt for the coolest happenings in the city. You can follow her musings on Twitter @BrookeViggiano .